The mission of All of Us Research Program is to accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.
This mission is carried out through three connected focus areas that are supported and made possible by a team that maintains a culture built around the program’s core values.

The All of Us Research Program has six strategic goals to help achieve its mission:
1. Enroll 1 million participants who reflect the diversity of the United States, cover the lifespan, and have shared all baseline elements. Of these, at least 500,000 participate in ongoing data donation opportunities.
2. Expand the data available for 1 million participants, to include surveys, health data streams, a whole genome sequence, environmental data, and physical measures.
3. Launch ancillary studies as a core and scalable capability, that expands the cohort and delivers new phenotypic, lifestyle, environmental, and biological data.
4. Establish a diverse global community of at least 10,000 researchers productively using All of Us data.
5. Incorporate participant return of value into data collections and assess its impact, including return of information to participants on genomic, electronic health record, and other health-related information.
6. Enable the full potential of the All of Us Research Program through organizational accountability, strategic and data-driven decision-making, effective core processes, and team capacity and development.
The All of Us Research Program is guided by a set of core values:
- Participation is open to all. People of every race, ethnicity, sex, gender, and sexual orientation are welcome. No health insurance is required. You can be healthy or have health issues. You can sign up directly through JoinAllofUs.org or through participating health care provider organizations.
- Participants reflect the rich diversity of the United States. To develop individualized plans for disease prevention and treatment, researchers need more data about the differences that make each of us unique. Having a diverse group of participants can lead to important breakthroughs. These discoveries may help make health care better for everyone.
- Participants are partners. Participants shape the program with their input and contribute to a project that may improve the health of future generations. They may also learn about their own health.
- Transparency earns trust. We inform participants about how their data are used, accessed, and shared. Participants can choose how much information to share.
- Participants have access to their information. All of Us lets participants see their own information and records.
- Data are broadly accessible for research purposes. All of Us makes information about participants as a group available in a public database. Everyone can explore the database or use it to make discoveries. Data from individual participants are also available, but only for researchers who apply and are approved. Any personal information that identifies a participant, such as name or address, is removed from data that researchers can access.
- Security and privacy are of highest importance. Data are stored in a secure, cloud-based database. All systems meet the requirements of the Federal Information Security Management Act. Ongoing security tests help protect participant data. Learn more about how the All of Us Research Program protects data and privacy.
- The program will be a catalyst for positive change in research. Working together, All of Us researchers, partners, and participants can build a better future for health research and care.
Precision Medicine and All of Us
Precision medicine is individualized care that considers the environment, lifestyle, family health history, and genetic makeup of a patient. It acknowledges that certain treatments work differently for people with different backgrounds, treats patients as individuals, and can reduce health care costs by providing the right treatment the first time. Learn more about precision medicine in this video from All of Us: